Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice

Pridopidine is currently under clinical development for Huntington disease (HD), with on-going studies to better characterize its therapeutic benefit and mode of action. Pridopidine was administered either prior to the appearance of disease phenotypes or in advanced stages of disease in the YAC128 m...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Garcia-Miralles, Marta, Geva, Michal, Tan, Jing Ying, Yusof, Nur Amirah Binte Mohammad, Cha, Yoonjeong, Kusko, Rebecca, Tan, Liang Juin, Xu, Xiaohong, Grossman, Iris, Orbach, Aric, Hayden, Michael R., Pouladi, Mahmoud A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752291/
https://ncbi.nlm.nih.gov/pubmed/29212949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95665
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