Histone H3 methylation links DNA damage detection to activation of the Tip60 tumor suppressor

Por Sun, Yingli, Jiang, Xiaofeng, Xu, Ye, Ayrapetov, Marina K., Moreau, Lisa A., Whetstine, Johnathan R., Price, Brendan D.
Publicado em 2009

Inhibition of the Nedd8 system sensitizes cells to DNA Inter-strand crosslinking agents

Por Kee, Younghoon, Huang, Min, Chang, Sophia, Moreau, Lisa A., Park, Eunmi, Smith, Peter G., D’Andrea, Alan D.
Publicado em 2012

Inactivation of Uaf1 Causes Defective Homologous Recombination and Early Embryonic Lethality in Mice

Por Park, Eunmi, Kim, Jung Min, Primack, Benjamin, Weinstock, David M., Moreau, Lisa A., Parmar, Kalindi, D'Andrea, Alan D.
Publicado em 2013

RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

Por Xie, Jenny, Kim, Hyungjin, Moreau, Lisa A., Puhalla, Shannon, Garber, Judy, Al Abo, Muthana, Takeda, Shunichi, D’Andrea, Alan D.
Publicado no J Clin Invest (2015)

RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites

Por Sobhian, Bijan, Shao, Genze, Lilli, Dana R., Culhane, Aedín C., Moreau, Lisa A., Xia, Bing, Livingston, David M., Greenberg, Roger A.
Publicado em 2007

Fanconi anemia pathway–deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated

Por Kennedy, Richard D., Chen, Clark C., Stuckert, Patricia, Archila, Elyse M., De la Vega, Michelle A., Moreau, Lisa A., Shimamura, Akiko, D’Andrea, Alan D.
Publicado em 2007

Loss of the Epigenetic Tumor Suppressor SNF5 Leads to Cancer without Genomic Instability

Por McKenna, Elizabeth S., Sansam, Courtney G., Cho, Yoon-Jae, Greulich, Heidi, Evans, Julia A., Thom, Christopher S., Moreau, Lisa A., Biegel, Jaclyn A., Pomeroy, Scott L., Roberts, Charles W. M.
Publicado em 2008

Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays

Por George, Rani E., Attiyeh, Edward F., Li, Shuli, Moreau, Lisa A., Neuberg, Donna, Li, Cheng, Fox, Edward A., Meyerson, Matthew, Diller, Lisa, Fortina, Paolo, Look, A. Thomas, Maris, John M.
Publicado em 2007

Biallelic Mutations in BRCA1 Cause a New Fanconi Anemia Subtype

Por Sawyer, Sarah L., Tian, Lei, Kähkönen, Marketta, Schwartzentruber, Jeremy, Kircher, Martin, Majewski, Jacek, Dyment, David A., Innes, A. Micheil, Boycott, Kym M., Moreau, Lisa A., Moilanen, Jukka S., Greenberg, Roger A.
Publicado no Cancer Discov (2014)

COMPROMISED CDK1 ACTIVITY SENSITIZES BRCA-PROFICIENT CANCERS TO PARP INHIBITION

Por Johnson, Neil, Li, Yu-Chen, Walton, Zandra E., Cheng, Katherine A., Li, Danan, Rodig, Scott J., Moreau, Lisa A., Unitt, Christine, Bronson, Roderick T., Thomas, Huw D., Newell, David R., D’Andrea, Alan D., Curtin, Nicola J., Wong, Kwok-Kin, Shapiro, Geoffrey I.
Publicado em 2011

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

Por Gutierrez, Alejandro, Sanda, Takaomi, Grebliunaite, Ruta, Carracedo, Arkaitz, Salmena, Leonardo, Ahn, Yebin, Dahlberg, Suzanne, Neuberg, Donna, Moreau, Lisa A., Winter, Stuart S., Larson, Richard, Zhang, Jianhua, Protopopov, Alexei, Chin, Lynda, Pandolfi, Pier Paolo, Silverman, Lewis B., Hunger, Stephen P., Sallan, Stephen E., Look, A. Thomas
Publicado em 2009

Overcoming reprogramming resistance of Fanconi anemia cells

Por Müller, Lars U. W., Milsom, Michael D., Harris, Chad E., Vyas, Rutesh, Brumme, Kristina M., Parmar, Kalindi, Moreau, Lisa A., Schambach, Axel, Park, In-Hyun, London, Wendy B., Strait, Kelly, Schlaeger, Thorsten, DeVine, Alexander L., Grassman, Elke, D'Andrea, Alan, Daley, George Q., Williams, David A.
Publicado em 2012

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

Por Johnson, Neil, Johnson, Shawn F., Yao, Wei, Li, Yu-Chen, Choi, Young-Eun, Bernhardy, Andrea J., Wang, Yifan, Capelletti, Marzia, Sarosiek, Kristopher A., Moreau, Lisa A., Chowdhury, Dipanjan, Wickramanayake, Anneka, Harrell, Maria I., Liu, Joyce F., D’Andrea, Alan D., Miron, Alexander, Swisher, Elizabeth M., Shapiro, Geoffrey I.
Publicado em 2013

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

Por Kentsis, Alex, Reed, Casie, Rice, Kim L., Sanda, Takaomi, Rodig, Scott J., Tholouli, Eleni, Christie, Amanda, Valk, Peter J.M., Delwel, Ruud, Ngo, Vu, Kutok, Jeffery L., Dahlberg, Suzanne E., Moreau, Lisa A., Byers, Richard J., Christensen, James G., Woude, George Vande, Licht, Jonathan D., Kung, Andrew L., Staudt, Louis M., Look, A. Thomas
Publicado em 2012

Emi1 Maintains Genomic Integrity during Zebrafish Embryogenesis and Cooperates with p53 in Tumor Suppression

Por Rhodes, Jennifer, Amsterdam, Adam, Sanda, Takaomi, Moreau, Lisa A., McKenna, Keith, Heinrichs, Stefan, Ganem, Neil J., Ho, Karen W., Neuberg, Donna S., Johnston, Adam, Ahn, Yebin, Kutok, Jeffery L., Hromas, Robert, Wray, Justin, Lee, Charles, Murphy, Carly, Radtke, Ina, Downing, James R., Fleming, Mark D., MacConaill, Laura E., Amatruda, James F., Gutierrez, Alejandro, Galinsky, Ilene, Stone, Richard M., Ross, Eric A., Pellman, David S., Kanki, John P., Look, A. Thomas
Publicado em 2009

CDK12 INHIBITION REVERSES DE NOVO AND ACQUIRED PARP INHIBITOR RESISTANCE IN BRCA WILD-TYPE AND MUTATED MODELS OF TRIPLE-NEGATIVE BREAST CANCER

Por Johnson, Shawn F., Cruz, Cristina, Greifenberg, Ann Katrin, Dust, Sofia, Stover, Daniel G., Chi, David, Primack, Benjamin, Cao, Shiliang, Bernhardy, Andrea J., Coulson, Rhiannon, Lazaro, Jean-Bernard, Kachupurakkal, Bose, Sun, Heather, Unitt, Christine, Moreau, Lisa A., Sarosiek, Kristopher A., Scaltriti, Maurizio, Juric, Dejan, Baselga, José, Richardson, Andrea L., Rodig, Scott J., D’Andrea, Alan D., Balmaña, Judith, Johnson, Neil, Geyer, Matthias, Serra, Violeta, Lim, Elgene, Shapiro, Geoffrey I.
Publicado no Cell Rep (2016)