Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage

Por Rao, Timsi, Gao, Rui, Takada, Saeko, Al Abo, Muthana, Chen, Xiang, Walters, Kylie J., Pommier, Yves, Aihara, Hideki
Publicado no Nucleic Acids Res (2016)

RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

Por Xie, Jenny, Kim, Hyungjin, Moreau, Lisa A., Puhalla, Shannon, Garber, Judy, Al Abo, Muthana, Takeda, Shunichi, D’Andrea, Alan D.
Publicado no J Clin Invest (2015)

TDP1 is critical for the repair of DNA breaks induced by sapacitabine, a nucleoside also targeting ATM- and BRCA-deficient tumors

Por Al Abo, Muthana, Sasanuma, Hiroyuki, Liu, Xiaojun, Rajapakse, Vinodh N, Huang, Shar-Yin, Kiselev, Evgeny, Takeda, Shunichi, Plunkett, William, Pommier, Yves
Publicado no Mol Cancer Ther (2017)

SLFN11 blocks stressed replication forks independently of ATR

Por Murai, Junko, Tang, Sai-Wen, Leo, Elisabetta, Baechler, Simone A, Redon, Christophe E., Zhang, Hongliang, Al Abo, Muthana, Rajapakse, Vinodh N, Nakamura, Eijiro, Miller Jenkins, Lisa M., Aladjem, Mirit I, Pommier, Yves
Publicado no Mol Cell (2018)