Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

Although the treatment of acute myeloid leukemia (AML) has improved significantly, more than half of all patients develop disease that is refractory to intensive chemotherapy(1,2). Functional genomics approaches offer a means to discover specific molecules mediating aberrant growth and survival of c...

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Hauptverfasser: Kentsis, Alex, Reed, Casie, Rice, Kim L., Sanda, Takaomi, Rodig, Scott J., Tholouli, Eleni, Christie, Amanda, Valk, Peter J.M., Delwel, Ruud, Ngo, Vu, Kutok, Jeffery L., Dahlberg, Suzanne E., Moreau, Lisa A., Byers, Richard J., Christensen, James G., Woude, George Vande, Licht, Jonathan D., Kung, Andrew L., Staudt, Louis M., Look, A. Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438345/
https://ncbi.nlm.nih.gov/pubmed/22683780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2819
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