Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

Although the treatment of acute myeloid leukemia (AML) has improved significantly, more than half of all patients develop disease that is refractory to intensive chemotherapy(1,2). Functional genomics approaches offer a means to discover specific molecules mediating aberrant growth and survival of c...

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Autores principales: Kentsis, Alex, Reed, Casie, Rice, Kim L., Sanda, Takaomi, Rodig, Scott J., Tholouli, Eleni, Christie, Amanda, Valk, Peter J.M., Delwel, Ruud, Ngo, Vu, Kutok, Jeffery L., Dahlberg, Suzanne E., Moreau, Lisa A., Byers, Richard J., Christensen, James G., Woude, George Vande, Licht, Jonathan D., Kung, Andrew L., Staudt, Louis M., Look, A. Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438345/
https://ncbi.nlm.nih.gov/pubmed/22683780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2819
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