The Requirement for Cyclin D Function in Tumor Maintenance

D-cyclins represent components of cell cycle machinery. To test the efficacy of targeting D-cyclins in cancer treatment, we engineered mouse strains which allow acute and global ablation of individual D-cyclins in a living animal. Ubiquitous shutdown of cyclin D1 or inhibition of cyclin D-associated...

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Hlavní autoři: Choi, Yoon Jong, Li, Xiaoyu, Hydbring, Per, Sanda, Takaomi, Stefano, Joanna, Christie, Amanda L., Signoretti, Sabina, Look, A. Thomas, Kung, Andrew L., von Boehmer, Harald, Sicinski, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487466/
https://ncbi.nlm.nih.gov/pubmed/23079655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.09.015
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