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Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells

BACKGROUND: Maintaining the correct balance of proliferation versus differentiation in retinal progenitor cells (RPCs) is essential for proper development of the retina. The cell cycle regulator cyclin D1 is expressed in RPCs, and mice with a targeted null allele at the cyclin D1 locus (Ccnd1(-/-))...

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Bibliografiske detaljer
Main Authors: Das, Gaurav, Choi, Yoon, Sicinski, Piotr, Levine, Edward M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694796/
https://ncbi.nlm.nih.gov/pubmed/19416500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-4-15
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