Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells

BACKGROUND: Maintaining the correct balance of proliferation versus differentiation in retinal progenitor cells (RPCs) is essential for proper development of the retina. The cell cycle regulator cyclin D1 is expressed in RPCs, and mice with a targeted null allele at the cyclin D1 locus (Ccnd1(-/-))...

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Bibliographic Details
Main Authors: Das, Gaurav, Choi, Yoon, Sicinski, Piotr, Levine, Edward M
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694796/
https://ncbi.nlm.nih.gov/pubmed/19416500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-4-15
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