Loss of the Epigenetic Tumor Suppressor SNF5 Leads to Cancer without Genomic Instability

There is a growing appreciation of the role that epigenetic alterations can play in oncogenesis. However, given the large number of genetic anomalies present in most cancers, it has been difficult to evaluate the extent to which epigenetic changes contribute to cancer. SNF5 (INI1/SMARCB1/BAF47) is a...

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Detalhes bibliográficos
Main Authors: McKenna, Elizabeth S., Sansam, Courtney G., Cho, Yoon-Jae, Greulich, Heidi, Evans, Julia A., Thom, Christopher S., Moreau, Lisa A., Biegel, Jaclyn A., Pomeroy, Scott L., Roberts, Charles W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577431/
https://ncbi.nlm.nih.gov/pubmed/18710953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00658-08
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