Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors

Emerging evidence demonstrates that subunits of the SWI/SNF chromatin remodeling complex are specifically mutated at high frequency in a variety of human cancer types. SNF5 (SMARCB1/INI1/BAF47), a core subunit of the SWI/SNF complex, is inactivated in the vast majority of rhabdoid tumors (RT), an ag...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McKenna, Elizabeth S., Tamayo, Pablo, Cho, Yoon-Jae, Tillman, Erik J., Mora-Blanco, E. Lorena, Sansam, Courtney G., Koellhoffer, Edward C., Pomeroy, Scott L., Roberts, Charles W.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359122/
https://ncbi.nlm.nih.gov/pubmed/22544318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20280
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados