טוען...
Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors
Emerging evidence demonstrates that subunits of the SWI/SNF chromatin remodeling complex are specifically mutated at high frequency in a variety of human cancer types. SNF5 (SMARCB1/INI1/BAF47), a core subunit of the SWI/SNF complex, is inactivated in the vast majority of rhabdoid tumors (RT), an ag...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Landes Bioscience
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359122/ https://ncbi.nlm.nih.gov/pubmed/22544318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20280 |
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