Overcoming reprogramming resistance of Fanconi anemia cells

Fanconi anemia (FA) is a recessive syndrome characterized by progressive fatal BM failure and chromosomal instability. FA cells have inactivating mutations in a signaling pathway that is critical for maintaining genomic integrity and protecting cells from the DNA damage caused by cross-linking agent...

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Hlavní autoři: Müller, Lars U. W., Milsom, Michael D., Harris, Chad E., Vyas, Rutesh, Brumme, Kristina M., Parmar, Kalindi, Moreau, Lisa A., Schambach, Axel, Park, In-Hyun, London, Wendy B., Strait, Kelly, Schlaeger, Thorsten, DeVine, Alexander L., Grassman, Elke, D'Andrea, Alan, Daley, George Q., Williams, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369681/
https://ncbi.nlm.nih.gov/pubmed/22371882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-408674
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