Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - a missed opportunity

Por Perez, Dominique R., Sklar, Larry A., Chigaev, Alexandre, Matlawska-Wasowska, Ksenia
Publicado no Semin Cancer Biol (2020)

Macrophage and NK-mediated Killing of Precursor-B Acute Lymphoblastic Leukemia Cells Targeted with a-Fucosylated Anti-CD19 Humanized Antibodies

Por Matlawska-Wasowska, Ksenia, Ward, Elizabeth, Stevens, Samuel, Wang, Yue, Herbst, Ronald, Winter, Stuart S., Wilson, Bridget S.
Publicado no Leukemia (2013)

Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia

Por Kinjyo, Ichiko, Matlawska-Wasowska, Ksenia, Chen, Xiaoru, Monks, Noel R., Burke, Patricia, Winter, Stuart S., Wilson, Bridget S.
Publicado no Pediatr Blood Cancer (2017)

Drugging DNA repair to target T-ALL cells

Por Dasgupta, Yashodhara, Golovine, Konstantin, Nieborowska-Skorska, Margaret, Luo, Li, Matlawska-Wasowska, Ksenia, Mullighan, Charles G., Skorski, Tomasz
Publicado no Leuk Lymphoma (2017)

The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis

Por Matlawska-Wasowska, Ksenia, Finn, Rebecca, Mustel, Ana, O'Byrne, Conor P, Baird, Alan W, Coffey, Eleanor T, Boyd, Aoife
Publicado em 2010

Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia

Por Erasmus, M. Frank, Matlawska-Wasowska, Ksenia, Kinjyo, Ichiko, Mahajan, Avanika, Winter, Stuart S., Xu, Li, Horowitz, Michael, Lidke, Diane S., Wilson, Bridget S.
Publicado no Sci Signal (2016)

Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia

Por Perez, Dominique R., Smagley, Yelena, Garcia, Matthew, Carter, Mark B., Evangelisti, Annette, Matlawska-Wasowska, Ksenia, Winter, Stuart S., Sklar, Larry A., Chigaev, Alexandre
Publicado no Oncotarget (2016)

Integration of Ruxolitinib into Dose-Intensified Therapy Targeted Against a Novel JAK2 F694L Mutation in B-precursor Acute Lymphoblastic Leukemia

Por Mayfield, Jodi R., Czuchlewski, David R., Gale, James M., Matlawska-Wasowska, Ksenia, Vasef, Mohammad A., Nickl, Christian, Pickett, Gavin, Ness, Scott A., Winter, Stuart S.
Publicado no Pediatr Blood Cancer (2016)

Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL

Por Kang, Huining, Sharma, Nitesh D., Nickl, Christian K., Devidas, Meenakshi, Loh, Mignon L., Hunger, Stephen P., Dunsmore, Kimberly P., Winter, Stuart S., Matlawska-Wasowska, Ksenia
Publicado no Biomark Res (2018)

Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy

Por Ksionda, Olga, Mues, Marsilius, Wandler, Anica M., Donker, Lisa, Tenhagen, Milou, Jun, Jesse, Ducker, Gregory S., Matlawska-Wasowska, Ksenia, Shannon, Kevin, Shokat, Kevan M., Roose, Jeroen P.
Publicado no PLoS One (2018)

Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent

Por Toma, Monika, Witusik-Perkowska, Monika, Szwed, Marzena, Stawski, Robert, Szemraj, Janusz, Drzewiecka, Malgorzata, Nieborowska-Skorska, Margaret, Radek, Maciej, Kolasa, Pawel, Matlawska-Wasowska, Ksenia, Sliwinski, Tomasz, Skorski, Tomasz
Publicado no Oncotarget (2018)

Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

Por Sharma, Nitesh D., Nickl, Christian K., Kang, Huining, Ornatowski, Wojciech, Brown, Roger, Ness, Scott A., Loh, Mignon L., Mullighan, Charles G., Winter, Stuart S., Hunger, Stephen P., Cannon, Judy L., Matlawska‐Wasowska, Ksenia
Publicado no Cancer Sci (2019)

High throughput flow cytometry identifies small molecule inhibitors for drug repurposing in T-ALL

Por Perez, Dominique R., Nickl, Christian K., Waller, Anna, Delgado-Martin, Cristina, Woods, Travis, Sharma, Nitesh D., Hermiston, Michelle L, Loh, Mignon L., Hunger, Stephen P., Winter, Stuart S., Chigaev, Alexandre, Edwards, Bruce, Sklar, Larry A., Matlawska-Wasowska, Ksenia
Publicado no SLAS Discov (2018)

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells

Por Sullivan-Reed, Katherine, Bolton-Gillespie, Elisabeth, Dasgupta, Yashodhara, Langer, Samantha, Siciliano, Micheal, Nieborowska-Skorska, Margaret, Hanamshet, Kritika, Belyaeva, Elizaveta A., Bernhardy, Andrea J., Lee, Jaewong, Moore, Morgan, Zhao, Huaqing, Valent, Peter, Matlawska-Wasowska, Ksenia, Müschen, Markus, Bhatia, Smita, Bhatia, Ravi, Johnson, Neil, Wasik, Mariusz A., Mazin, Alexander V., Skorski, Tomasz
Publicado no Cell Rep (2018)

MLL Rearrangements Impact Outcome in HOXA-deregulated T-lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

Por Matlawska-Wasowska, Ksenia, Kang, Huining, Devidas, Meenakshi, Wen, Ji, Harvey, Richard C., Nickl, Christian K., Ness, Scott A., Rusch, Michael, Li, Yongjin, Onozawa, Masahiro, Martinez, Carmen, Wood, Brent L., Asselin, Barbara L., Chen, I-Ming, Roberts, Kathryn G., Baruchel, André, Soulier, Jean, Dombret, Hervé, Zhang, Jinghui, Larson, Richard S., Raetz, Elizabeth A., Carroll, William L., Winick, Naomi J., Aplan, Peter D., Loh, Mignon L., Mullighan, Charles G., Hunger, Stephen P., Heerema, Nyla A., Carroll, Andrew J., Dunsmore, Kimberly P., Winter, Stuart S.
Publicado no Leukemia (2016)

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Por Matthijssens, Filip, Sharma, Nitesh D., Nysus, Monique, Nickl, Christian K., Kang, Huining, Perez, Dominique R., Lintermans, Beatrice, Van Loocke, Wouter, Roels, Juliette, Peirs, Sofie, Demoen, Lisa, Pieters, Tim, Reunes, Lindy, Lammens, Tim, De Moerloose, Barbara, Van Nieuwerburgh, Filip, Deforce, Dieter L., Cheung, Laurence C., Kotecha, Rishi S., Risseeuw, Martijn D.P., Van Calenbergh, Serge, Takarada, Takeshi, Yoneda, Yukio, van Delft, Frederik W., Lock, Richard B., Merkley, Seth D., Chigaev, Alexandre, Sklar, Larry A., Mullighan, Charles G., Loh, Mignon L., Winter, Stuart S., Hunger, Stephen P., Goossens, Steven, Castillo, Eliseo F., Ornatowski, Wojciech, Van Vlierberghe, Pieter, Matlawska-Wasowska, Ksenia
Publicado no J Clin Invest (2021)