Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

Activating mutations in cytokine receptors and transcriptional regulators govern aberrant signal transduction in T‐cell lineage acute lymphoblastic leukemia (T‐ALL). However, the roles played by suppressors of cytokine signaling remain incompletely understood. We examined the regulatory roles of sup...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Sharma, Nitesh D., Nickl, Christian K., Kang, Huining, Ornatowski, Wojciech, Brown, Roger, Ness, Scott A., Loh, Mignon L., Mullighan, Charles G., Winter, Stuart S., Hunger, Stephen P., Cannon, Judy L., Matlawska‐Wasowska, Ksenia
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549933/
https://ncbi.nlm.nih.gov/pubmed/30974024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14021
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