Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia

Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a recently described subtype of T-ALL characterized by a unique immunophenotype and genomic profile, as well as a high rate of induction failure. Frequent mutations in cytokine receptor and Janus kinase (JAK)/signal transducer and ac...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Maude, Shannon L., Dolai, Sibasish, Delgado-Martin, Cristina, Vincent, Tiffaney, Robbins, Alissa, Selvanathan, Arthavan, Ryan, Theresa, Hall, Junior, Wood, Andrew C., Tasian, Sarah K., Hunger, Stephen P., Loh, Mignon L., Mullighan, Charles G., Wood, Brent L., Hermiston, Michelle L., Grupp, Stephan A., Lock, Richard B., Teachey, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357583/
https://ncbi.nlm.nih.gov/pubmed/25645356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-580480
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