Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL

For children and young adults with T-lineage acute lymphoblastic leukemia (T-ALL), event free survival following relapse is < 10%. We recently showed that rearrangements of the mixed lineage leukemia gene (KMT2A-R) are associated with induction failure and an inferior survival in T-ALL. Because t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomark Res
Autori principali: Kang, Huining, Sharma, Nitesh D., Nickl, Christian K., Devidas, Meenakshi, Loh, Mignon L., Hunger, Stephen P., Dunsmore, Kimberly P., Winter, Stuart S., Matlawska-Wasowska, Ksenia
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Rapid Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107954/
https://ncbi.nlm.nih.gov/pubmed/30159143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0141-z
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi