The Partial Duplication of the 5′ Segment of KMT2A Revealed KMT2A-MLLT10 Rearrangement in a Boy with Acute Myeloid Leukemia

The duplication of 5′ segment of KMT2A is a rare molecular event in childhood leukemia, and the influence on prognosis is unknown. Here, we report on a boy who developed acute monocytic leukemia. Fluorescence in situ hybridization revealed the duplication of the 5′ segment with 2 normal alleles at K...

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Detalhes bibliográficos
Publicado no:Case Rep Pediatr
Main Authors: Fukushima, Hiroko, Nanmoku, Toru, Hosaka, Sho, Yamaki, Yuni, Kiyokawa, Nobutaka, Fukushima, Takashi, Sumazaki, Ryo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763053/
https://ncbi.nlm.nih.gov/pubmed/29445560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6257494
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