RAD52 as a Potential Target for Synthetic Lethality-Based Anticancer Therapies

di Toma, Monika, Sullivan-Reed, Katherine, Śliwiński, Tomasz, Skorski, Tomasz
Pubblicato in Cancers (Basel) (2019)

Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia

di Hewlett, Elizabeth, Toma, Monika, Sullivan-Reed, Katherine, Gordo, John, Sliwinski, Tomasz, Tulin, Alexei, Childers, Wayne E, Skorski, Tomasz
Pubblicato in Med Chem Res (2020)

Molecular basis of microhomology-mediated end-joining by purified full-length Polθ

di Black, Samuel J., Ozdemir, Ahmet Y., Kashkina, Ekaterina, Kent, Tatiana, Rusanov, Timur, Ristic, Dejan, Shin, Yeonoh, Suma, Antonio, Hoang, Trung, Chandramouly, Gurushankar, Siddique, Labiba A., Borisonnik, Nikita, Sullivan-Reed, Katherine, Mallon, Joseph S., Skorski, Tomasz, Carnevale, Vincenzo, Murakami, Katsuhiko S., Wyman, Claire, Pomerantz, Richard T.
Pubblicato in Nat Commun (2019)

Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ

di Black, Samuel J., Ozdemir, Ahmet Y., Kashkina, Ekaterina, Kent, Tatiana, Rusanov, Timur, Ristic, Dejan, Shin, Yeonoh, Suma, Antonio, Hoang, Trung, Chandramouly, Gurushankar, Siddique, Labiba A., Borisonnik, Nikita, Sullivan-Reed, Katherine, Mallon, Joseph S., Skorski, Tomasz, Carnevale, Vincenzo, Murakami, Katsuhiko S., Wyman, Claire, Pomerantz, Richard T.
Pubblicato in Nat Commun (2020)

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells

di Sullivan-Reed, Katherine, Bolton-Gillespie, Elisabeth, Dasgupta, Yashodhara, Langer, Samantha, Siciliano, Micheal, Nieborowska-Skorska, Margaret, Hanamshet, Kritika, Belyaeva, Elizaveta A., Bernhardy, Andrea J., Lee, Jaewong, Moore, Morgan, Zhao, Huaqing, Valent, Peter, Matlawska-Wasowska, Ksenia, Müschen, Markus, Bhatia, Smita, Bhatia, Ravi, Johnson, Neil, Wasik, Mariusz A., Mazin, Alexander V., Skorski, Tomasz
Pubblicato in Cell Rep (2018)

Tyrosine kinase inhibitor–induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors

di Maifrede, Silvia, Nieborowska-Skorska, Margaret, Sullivan-Reed, Katherine, Dasgupta, Yashodhara, Podszywalow-Bartnicka, Paulina, Le, Bac Viet, Solecka, Martyna, Lian, Zhaorui, Belyaeva, Elizaveta A., Nersesyan, Alina, Machnicki, Marcin M., Toma, Monika, Chatain, Nicolas, Rydzanicz, Malgorzata, Zhao, Huaqing, Jelinek, Jaroslav, Piwocka, Katarzyna, Sliwinski, Tomasz, Stoklosa, Tomasz, Ploski, Rafal, Fischer, Thomas, Sykes, Stephen M., Koschmieder, Steffen, Bullinger, Lars, Valent, Peter, Wasik, Mariusz A., Huang, Jian, Skorski, Tomasz
Pubblicato in Blood (2018)

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

di Le, Bac Viet, Podszywalow-Bartnicka, Paulina, Maifrede, Silvia, Sullivan-Reed, Katherine, Nieborowska-Skorska, Margaret, Golovine, Konstantin, Yao, Juo-Chin, Nejati, Reza, Cai, Kathy Q., Caruso, Lisa Beatrice, Swatler, Julian, Dabrowski, Michal, Lian, Zhaorui, Valent, Peter, Paietta, Elisabeth M., Levine, Ross L., Fernandez, Hugo F., Tallman, Martin S., Litzow, Mark R., Huang, Jian, Challen, Grant A., Link, Daniel, Tempera, Italo, Wasik, Mariusz A., Piwocka, Katarzyna, Skorski, Tomasz
Pubblicato in Cell Rep (2020)