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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - a missed opportunity

While current treatment regimens for acute leukemia can dramatically improve patient survival, there remains room for improvement. Due to its roles in cell differentiation, cell survival, and apoptotic signaling, modulation of the cyclic AMP (cAMP) pathway has provided a meaningful target in hematol...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Perez, Dominique R., Sklar, Larry A., Chigaev, Alexandre, Matlawska-Wasowska, Ksenia
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415530/
https://ncbi.nlm.nih.gov/pubmed/32044470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.02.004
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