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A high throughput flow cytometry assay for identification of inhibitors of 3’, 5’-cyclic adenosine monophosphate efflux

Assays to identify small molecule inhibitors of cell transporters have long been used to develop potential therapies for reversing drug resistance in cancer cells. In flow cytometry, these approaches rely on the use of fluorescent substrates of transporters. Compounds which prevent the loss of cell...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Perez, Dominique, Simons, Peter C., Smagley, Yelena, Sklar, Larry A., Chigaev, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269090/
https://ncbi.nlm.nih.gov/pubmed/27316999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3673-1_15
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