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High-throughput flow cytometry (HTFC) drug combination discovery with novel synergy analysis software, SynScreen

Classical therapeutic regimens are subject to toxicity, low efficacy, and/or the development of drug resistance. Thus, the discovery of synergistic drug combinations would permit treatment with lower, tolerable dosages of each agent and restored sensitivity. We describe the development and use of th...

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Dades bibliogràfiques
Publicat a:SLAS Discov
Autors principals: Perez, Dominique R, Edwards, Bruce S, Sklar, Larry A, Chigaev, Alexandre
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363001/
https://ncbi.nlm.nih.gov/pubmed/29842834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218775913
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