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High-throughput flow cytometry (HTFC) drug combination discovery with novel synergy analysis software, SynScreen

Classical therapeutic regimens are subject to toxicity, low efficacy, and/or the development of drug resistance. Thus, the discovery of synergistic drug combinations would permit treatment with lower, tolerable dosages of each agent and restored sensitivity. We describe the development and use of th...

詳細記述

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書誌詳細
出版年:SLAS Discov
主要な著者: Perez, Dominique R, Edwards, Bruce S, Sklar, Larry A, Chigaev, Alexandre
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363001/
https://ncbi.nlm.nih.gov/pubmed/29842834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218775913
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