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High-throughput flow cytometry (HTFC) drug combination discovery with novel synergy analysis software, SynScreen

Classical therapeutic regimens are subject to toxicity, low efficacy, and/or the development of drug resistance. Thus, the discovery of synergistic drug combinations would permit treatment with lower, tolerable dosages of each agent and restored sensitivity. We describe the development and use of th...

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Publicado en:SLAS Discov
Autores principales: Perez, Dominique R, Edwards, Bruce S, Sklar, Larry A, Chigaev, Alexandre
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363001/
https://ncbi.nlm.nih.gov/pubmed/29842834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218775913
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