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Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
We developed a platform combining fluorogen-activating protein (FAP) technology with high-throughput flow cytometry to detect real-time protein trafficking to and from the plasma membrane in living cells. The hybrid platform facilitates drug discovery for trafficking receptors such as G protein-coup...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463215/ https://ncbi.nlm.nih.gov/pubmed/22767611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.079897 |
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