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Real Time Detection of Protein Trafficking with High Throughput Flow Cytometry (HTFC) and Fluorogen Activating Protein (FAP) Base Biosensor

We combined fluorogen activating protein (FAP) technology with high-throughput flow cytometry to detect real-time protein trafficking to and from the plasma membrane in living cells. The hybrid platform allows drug discovery for trafficking receptors, such as G-protein coupled receptors, receptor ty...

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Detalhes bibliográficos
Main Authors: Wu, Yang, Tapia, Phillip H., Jarvik, Jonathan, Waggoner, Alan S., Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961059/
https://ncbi.nlm.nih.gov/pubmed/24510772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142956.cy0943s67
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