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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - a missed opportunity

While current treatment regimens for acute leukemia can dramatically improve patient survival, there remains room for improvement. Due to its roles in cell differentiation, cell survival, and apoptotic signaling, modulation of the cyclic AMP (cAMP) pathway has provided a meaningful target in hematol...

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Detalles Bibliográficos
Publicado en:Semin Cancer Biol
Main Authors: Perez, Dominique R., Sklar, Larry A., Chigaev, Alexandre, Matlawska-Wasowska, Ksenia
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415530/
https://ncbi.nlm.nih.gov/pubmed/32044470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.02.004
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