cGMP-dependent protein kinase from Toxoplasma gondii: functional expression in E. coli and molecular characterization

著者: McFarland, Caitlin J, Nickl, Christian K, Osborne, Brent W, Sarkar, Indra Neil, Dostmann, Wolfgang R
出版事項 2011

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iα inhibit NO-induced cerebral dilation

著者: Dostmann, Wolfgang R. G., Taylor, Mark S., Nickl, Christian K., Brayden, Joseph E., Frank, Ronald, Tegge, Werner J.
出版事項 2000

Adenosine analogue–oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIα)

著者: Lavogina, Darja, Nickl, Christian K., Enkvist, Erki, Raidaru, Gerda, Lust, Marje, Vaasa, Angela, Uri, Asko, Dostmann, Wolfgang R.
出版事項 2010

DIRECT MODULATION OF THE PROTEIN KINASE A CATALYTIC SUBUNIT α BY GROWTH FACTOR RECEPTOR TYROSINE KINASES

著者: Caldwell, George B., Howe, Alan K., Nickl, Christian K., Dostmann, Wolfgang R., Ballif, Bryan A., Deming, Paula B.
出版事項 2012

(D)-amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Iα

著者: Nickl, Christian K., Raidas, Shiv Kumar, Zhao, Hong, Sausbier, Matthias, Ruth, Peter, Tegge, Werner, Brayden, Joseph E., Dostmann, Wolfgang R.
出版事項 2009

Integration of Ruxolitinib into Dose-Intensified Therapy Targeted Against a Novel JAK2 F694L Mutation in B-precursor Acute Lymphoblastic Leukemia

著者: Mayfield, Jodi R., Czuchlewski, David R., Gale, James M., Matlawska-Wasowska, Ksenia, Vasef, Mohammad A., Nickl, Christian, Pickett, Gavin, Ness, Scott A., Winter, Stuart S.
出版年 Pediatr Blood Cancer (2016)

Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL

著者: Kang, Huining, Sharma, Nitesh D., Nickl, Christian K., Devidas, Meenakshi, Loh, Mignon L., Hunger, Stephen P., Dunsmore, Kimberly P., Winter, Stuart S., Matlawska-Wasowska, Ksenia
出版年 Biomark Res (2018)

Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication

著者: Osborne, Brent W., Wu, Jian, McFarland, Caitlin J., Nickl, Christian K., Sankaran, Banumathi, Casteel, Darren E., Woods, Virgil L., Kornev, Alexandr P., Taylor, Susan S., Dostmann, Wolfgang R.
出版事項 2011

Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

著者: Sharma, Nitesh D., Nickl, Christian K., Kang, Huining, Ornatowski, Wojciech, Brown, Roger, Ness, Scott A., Loh, Mignon L., Mullighan, Charles G., Winter, Stuart S., Hunger, Stephen P., Cannon, Judy L., Matlawska‐Wasowska, Ksenia
出版年 Cancer Sci (2019)

High throughput flow cytometry identifies small molecule inhibitors for drug repurposing in T-ALL

著者: Perez, Dominique R., Nickl, Christian K., Waller, Anna, Delgado-Martin, Cristina, Woods, Travis, Sharma, Nitesh D., Hermiston, Michelle L, Loh, Mignon L., Hunger, Stephen P., Winter, Stuart S., Chigaev, Alexandre, Edwards, Bruce, Sklar, Larry A., Matlawska-Wasowska, Ksenia
出版年 SLAS Discov (2018)

Brain cell type-specific enhancer-promoter interactome maps and disease risk association

著者: Nott, Alexi, Holtman, Inge R., Coufal, Nicole G., Schlachetzki, Johannes C.M., Yu, Miao, Hu, Rong, Han, Claudia Z., Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P., O’Connor, Carolyn, Nickl, Christian K., Schafer, Simon T., Shen, Zeyang, Rissman, Robert A., Brewer, James B., Gosselin, David, Gonda, David D., Levy, Michael L., Rosenfeld, Michael G., McVicker, Graham, Gage, Fred H., Ren, Bing, Glass, Christopher K.
出版年 Science (2019)

MLL Rearrangements Impact Outcome in HOXA-deregulated T-lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

著者: Matlawska-Wasowska, Ksenia, Kang, Huining, Devidas, Meenakshi, Wen, Ji, Harvey, Richard C., Nickl, Christian K., Ness, Scott A., Rusch, Michael, Li, Yongjin, Onozawa, Masahiro, Martinez, Carmen, Wood, Brent L., Asselin, Barbara L., Chen, I-Ming, Roberts, Kathryn G., Baruchel, André, Soulier, Jean, Dombret, Hervé, Zhang, Jinghui, Larson, Richard S., Raetz, Elizabeth A., Carroll, William L., Winick, Naomi J., Aplan, Peter D., Loh, Mignon L., Mullighan, Charles G., Hunger, Stephen P., Heerema, Nyla A., Carroll, Andrew J., Dunsmore, Kimberly P., Winter, Stuart S.
出版年 Leukemia (2016)

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

著者: Matthijssens, Filip, Sharma, Nitesh D., Nysus, Monique, Nickl, Christian K., Kang, Huining, Perez, Dominique R., Lintermans, Beatrice, Van Loocke, Wouter, Roels, Juliette, Peirs, Sofie, Demoen, Lisa, Pieters, Tim, Reunes, Lindy, Lammens, Tim, De Moerloose, Barbara, Van Nieuwerburgh, Filip, Deforce, Dieter L., Cheung, Laurence C., Kotecha, Rishi S., Risseeuw, Martijn D.P., Van Calenbergh, Serge, Takarada, Takeshi, Yoneda, Yukio, van Delft, Frederik W., Lock, Richard B., Merkley, Seth D., Chigaev, Alexandre, Sklar, Larry A., Mullighan, Charles G., Loh, Mignon L., Winter, Stuart S., Hunger, Stephen P., Goossens, Steven, Castillo, Eliseo F., Ornatowski, Wojciech, Van Vlierberghe, Pieter, Matlawska-Wasowska, Ksenia
出版年 J Clin Invest (2021)