Brain cell type-specific enhancer-promoter interactome maps and disease risk association

Non-coding genetic variation is a major driver of phenotypic diversity, but functional interpretation is challenging. To better understand common genetic variation associated with brain diseases, we defined non-coding regulatory regions for major cell types of the human brain. Whereas psychiatric di...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Nott, Alexi, Holtman, Inge R., Coufal, Nicole G., Schlachetzki, Johannes C.M., Yu, Miao, Hu, Rong, Han, Claudia Z., Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P., O’Connor, Carolyn, Nickl, Christian K., Schafer, Simon T., Shen, Zeyang, Rissman, Robert A., Brewer, James B., Gosselin, David, Gonda, David D., Levy, Michael L., Rosenfeld, Michael G., McVicker, Graham, Gage, Fred H., Ren, Bing, Glass, Christopher K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028213/
https://ncbi.nlm.nih.gov/pubmed/31727856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay0793
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