Brain cell type-specific enhancer-promoter interactome maps and disease risk association

Non-coding genetic variation is a major driver of phenotypic diversity, but functional interpretation is challenging. To better understand common genetic variation associated with brain diseases, we defined non-coding regulatory regions for major cell types of the human brain. Whereas psychiatric di...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Science
Main Authors: Nott, Alexi, Holtman, Inge R., Coufal, Nicole G., Schlachetzki, Johannes C.M., Yu, Miao, Hu, Rong, Han, Claudia Z., Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P., O’Connor, Carolyn, Nickl, Christian K., Schafer, Simon T., Shen, Zeyang, Rissman, Robert A., Brewer, James B., Gosselin, David, Gonda, David D., Levy, Michael L., Rosenfeld, Michael G., McVicker, Graham, Gage, Fred H., Ren, Bing, Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028213/
https://ncbi.nlm.nih.gov/pubmed/31727856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay0793
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados