Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication

Por Dostmann, Wolfgang R, Osborne, Brent W
Publicado em 2011

Sub-Nanomolar Sensitivity of Nitric Oxide Mediated Regulation of cGMP and Vasomotor Reactivity in Vascular Smooth Muscle

Por Held, Kara F., Dostmann, Wolfgang R.
Publicado em 2012

Real-Time Monitoring the Spatiotemporal Dynamics of Intracellular cGMP in Vascular Smooth Muscle Cells

Por Held, Kara F., Dostmann, Wolfgang R.
Publicado no Methods Mol Biol (2013)

The Switch Helix: A putative combinatorial relay for interprotomer communication in cGMP-dependent protein kinase

Por Moon, Thomas M., Osborne, Brent W., Dostmann, Wolfgang R.
Publicado em 2013

A structural analysis of the regulatory domain from the cGMP-dependent protein kinase Iα

Por Osborne, Brent W, Menke, Andrew T, Blumenthal, Donald K, Dostmann, Wolfgang R
Publicado em 2011

Mode of Action of cGMP-dependent Protein Kinase-specific Inhibitors Probed by Photoaffinity Cross-linking Mass Spectrometry

Por Pinkse, Martijn W. H., Rijkers, Dirk T. S., Dostmann, Wolfgang R., Heck, Albert J. R.
Publicado em 2009

Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors

Por Nausch, Lydia W. M., Ledoux, Jonathan, Bonev, Adrian D., Nelson, Mark T., Dostmann, Wolfgang R.
Publicado em 2008

cGMP-dependent protein kinase from Toxoplasma gondii: functional expression in E. coli and molecular characterization

Por McFarland, Caitlin J, Nickl, Christian K, Osborne, Brent W, Sarkar, Indra Neil, Dostmann, Wolfgang R
Publicado em 2011

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iα inhibit NO-induced cerebral dilation

Por Dostmann, Wolfgang R. G., Taylor, Mark S., Nickl, Christian K., Brayden, Joseph E., Frank, Ronald, Tegge, Werner J.
Publicado em 2000

Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator

Por Honda, Akira, Adams, Stephen R., Sawyer, Carolyn L., Lev-Ram, Varda, Tsien, Roger Y., Dostmann, Wolfgang R. G.
Publicado em 2001

Nitric Oxide Promotes Airway Epithelial Wound Repair through Enhanced Activation of MMP-9

Por Bove, Peter F., Wesley, Umadevi V., Greul, Anne-Katrin, Hristova, Milena, Dostmann, Wolfgang R., van der Vliet, Albert
Publicado em 2007

Adenosine analogue–oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIα)

Por Lavogina, Darja, Nickl, Christian K., Enkvist, Erki, Raidaru, Gerda, Lust, Marje, Vaasa, Angela, Uri, Asko, Dostmann, Wolfgang R.
Publicado em 2010

DIRECT MODULATION OF THE PROTEIN KINASE A CATALYTIC SUBUNIT α BY GROWTH FACTOR RECEPTOR TYROSINE KINASES

Por Caldwell, George B., Howe, Alan K., Nickl, Christian K., Dostmann, Wolfgang R., Ballif, Bryan A., Deming, Paula B.
Publicado em 2012

Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart

Por Miller, Clint L., Cai, Yujun, Oikawa, Masayoshi, Thomas, Tamlyn, Dostmann, Wolfgang R., Zaccolo, Manuela, Fujiwara, Keigi, Yan, Chen
Publicado em 2011

(D)-amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Iα

Por Nickl, Christian K., Raidas, Shiv Kumar, Zhao, Hong, Sausbier, Matthias, Ruth, Peter, Tegge, Werner, Brayden, Joseph E., Dostmann, Wolfgang R.
Publicado em 2009

Synthetic peptides as cGMP-independent activators of cGMP-dependent protein kinase Iα

Por Moon, Thomas M., Tykocki, Nathan R., Sheehe, Jessica L., Osborne, Brent W., Tegge, Werner, Brayden, Joseph E., Dostmann, Wolfgang R.
Publicado no Chem Biol (2015)

Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors

Por Batchelor, Andrew M., Bartus, Katalin, Reynell, Clare, Constantinou, Sophie, Halvey, Edward J., Held, Kara F., Dostmann, Wolfgang R., Vernon, Jeffrey, Garthwaite, John
Publicado em 2010

Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication

Por Osborne, Brent W., Wu, Jian, McFarland, Caitlin J., Nickl, Christian K., Sankaran, Banumathi, Casteel, Darren E., Woods, Virgil L., Kornev, Alexandr P., Taylor, Susan S., Dostmann, Wolfgang R.
Publicado em 2011

Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis

Por Arora, Kavisha, Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Ren, Aixia, Yarlagadda, Sunitha, Dostmann, Wolfgang R., Adebiyi, Adebowale, Haberman, Yael, Denson, Lee A., Wang, Xusheng, Naren, Anjaparavanda P.
Publicado no Am J Pathol (2015)

cGMP-dependent protein kinase Iα associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake

Por Steiner, Jennifer A, Carneiro, Ana Marin D, Wright, Jane, Matthies, Heinrich JG, Prasad, Harish C, Nicki, Christian K, Dostmann, Wolfgang R, Buchanan, Carrie C, Corbin, Jackie D, Francis, Sharron H, Blakely, Randy D
Publicado em 2009