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Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors

Nitric oxide (NO) functions as a diffusible transmitter in most tissues of the body and exerts its effects by binding to receptors harboring a guanylyl cyclase transduction domain, resulting in cGMP accumulation in target cells. Despite its widespread importance, very little is known about how this...

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Detalhes bibliográficos
Main Authors: Batchelor, Andrew M., Bartus, Katalin, Reynell, Clare, Constantinou, Sophie, Halvey, Edward J., Held, Kara F., Dostmann, Wolfgang R., Vernon, Jeffrey, Garthwaite, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009818/
https://ncbi.nlm.nih.gov/pubmed/21135206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013147107
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