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Inhibition of nitric oxide-activated guanylyl cyclase by calmodulin antagonists

BACKGROUND AND PURPOSE: Nitric oxide (NO) controls numerous physiological processes by activation of its receptor, guanylyl cyclase (sGC), leading to the accumulation of 3′-5′ cyclic guanosine monophosphate (cGMP). Ca(2+)-calmodulin (CaM) regulates both NO synthesis by NO synthase and cGMP hydrolysi...

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Detalhes bibliográficos
Main Authors: James, LR, Griffiths, CH, Garthwaite, J, Bellamy, TC
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795212/
https://ncbi.nlm.nih.gov/pubmed/19845679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00416.x
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