ICOS is required for the generation of both central and effector CD4(+) memory T‐cell populations following acute bacterial infection

Por Marriott, Clare L., Carlesso, Gianluca, Herbst, Ronald, Withers, David R.
Publicado no Eur J Immunol (2015)

B-cell targeted therapeutics in clinical development

Por Blüml, Stephan, McKeever, Kathleen, Ettinger, Rachel, Smolen, Josef, Herbst, Ronald
Publicado em 2013

Inebilizumab, a B Cell-Depleting Anti-CD19 Antibody for the Treatment of Autoimmune Neurological Diseases: Insights from Preclinical Studies

Por Chen, Ding, Gallagher, Sandra, Monson, Nancy L., Herbst, Ronald, Wang, Yue
Publicado no J Clin Med (2016)

Macrophage and NK-mediated Killing of Precursor-B Acute Lymphoblastic Leukemia Cells Targeted with a-Fucosylated Anti-CD19 Humanized Antibodies

Por Matlawska-Wasowska, Ksenia, Ward, Elizabeth, Stevens, Samuel, Wang, Yue, Herbst, Ronald, Winter, Stuart S., Wilson, Bridget S.
Publicado no Leukemia (2013)

Loss of Immune Tolerance Is Controlled by ICOS in Sle1 Mice

Por Mittereder, Nanette, Kuta, Ellen, Bhat, Geetha, Dacosta, Karma, Cheng, Lily I., Herbst, Ronald, Carlesso, Gianluca
Publicado no J Immunol (2016)

CAT-8015: A Second-generation Pseudomonas Exotoxin A-Based Immunotherapy Targeting CD22 -Expressing Hematological Malignancies

Por Alderson, Ralph F., Kreitman, Robert J., Chen, Tianling, Yeung, Peter, Herbst, Ronald, Fox, Judy A., Pastan, Ira
Publicado em 2009

CD19 and CD32b Differentially Regulate Human B Cell Responsiveness

Por Karnell, Jodi L., Dimasi, Nazzareno, Karnell, Fredrick G., Fleming, Ryan, Kuta, Ellen, Wilson, Mildred, Wu, Herren, Gao, Changshou, Herbst, Ronald, Ettinger, Rachel
Publicado em 2014

Single Dose of Glycoengineered Anti-CD19 Antibody (MEDI551) Disrupts Experimental Autoimmune Encephalomyelitis by Inhibiting Pathogenic Adaptive Immune Responses in the Bone Marrow...

Por Chen, Ding, Blazek, Monica, Ireland, Sara, Ortega, Sterling, Kong, Xiangmei, Meeuwissen, Anouk, Stowe, Ann, Carter, Laura, Wang, Yue, Herbst, Ronald, Monson, Nancy L.
Publicado no J Immunol (2014)

Germinal Center B Cell Depletion Diminishes CD4(+) Follicular T Helper Cells in Autoimmune Mice

Por Yusuf, Isharat, Stern, Jessica, McCaughtry, Tom M., Gallagher, Sandra, Sun, Hong, Gao, Changshou, Tedder, Thomas, Carlesso, Gianluca, Carter, Laura, Herbst, Ronald, Wang, Yue
Publicado em 2014

RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function

Por Tian, Jane, Huang, Kelly, Krishnan, Subramaniam, Svabek, Catherine, Rowe, Daniel C., Brewah, Yambasu, Sanjuan, Miguel, Patera, Andriani C., Kolbeck, Roland, Herbst, Ronald, Sims, Gary P.
Publicado em 2013

Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells

Por Nyborg, Andrew C, Zacco, Anna, Ettinger, Rachel, Jack Borrok, M, Zhu, Jie, Martin, Tom, Woods, Rob, Kiefer, Christine, Bowen, Michael A, Suzanne Cohen, E., Herbst, Ronald, Wu, Herren, Coats, Steven
Publicado no Cell Mol Immunol (2016)

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection

Por Miller, Allison L., Sims, Gary P., Brewah, Yambasu A., Rebelatto, Marlon C., Kearley, Jennifer, Benjamin, Ebony, Keller, Ashley E., Brohawn, Philip, Herbst, Ronald, Coyle, Anthony J., Humbles, Alison A., Kolbeck, Roland
Publicado em 2012

Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation

Por Karnell, Jodi L., Karnell, Fredrick G., Stephens, Geoffrey L., Rajan, Bhargavi, Morehouse, Chris, Li, Ying, Swerdlow, Bonnie, Wilson, Mildred, Goldbach-Mansky, Raphaela, Groves, Christopher, Coyle, Anthony J., Herbst, Ronald, Ettinger, Rachel
Publicado em 2011

Safety and tolerability of an anti-CD19 monoclonal antibody, MEDI-551, in subjects with systemic sclerosis: a phase I, randomized, placebo-controlled, escalating single-dose study

Por Schiopu, Elena, Chatterjee, Soumya, Hsu, Vivien, Flor, Armando, Cimbora, Daniel, Patra, Kaushik, Yao, Wenliang, Li, Jing, Streicher, Katie, McKeever, Kathleen, White, Barbara, Katz, Eliezer, Drappa, Jorn, Sweeny, Sarah, Herbst, Ronald
Publicado no Arthritis Res Ther (2016)

Cell Distance Mapping identifies functional T follicular helper cells in inflamed human renal tissue

Por Liarski, Vladimir M., Kaverina, Natalya, Chang, Anthony, Brandt, Daniel, Yanez, Denisse, Talasnik, Lauren, Carlesso, Gianluca, Herbst, Ronald, Utset, Tammy O., Labno, Christine, Peng, Yahui, Jiang, Yulei, Giger, Maryellen L., Clark, Marcus R.
Publicado em 2014

Genomic-Based High Throughput Screening Identifies Small Molecules That Differentially Inhibit the Antiviral and Immunomodulatory Effects of IFN-α

Por Chen, Bo, Zong, Qin, Cibotti, Ricardo, Morris, Chad, Castaneda, Juana, Naiman, Brian, Liu, Derong, Glodek, Anna, Sims, Gary P, Herbst, Ronald, Horrigan, Stephen K, Kiener, Peter A, Soppet, Dan, Coyle, Anthony J, Audoly, Laurent
Publicado em 2008

Safety and disease response to MEDI-551, an anti-CD19 antibody, in chronic lymphocytic leukemia patients previously treated with rituximab

Por Forero, Andres, Hamadani, Mehdi, Kipps, Thomas, Fanale, Michelle, Cuneo, Antonio, Perez de Oteyza, Jaime, Gladstone, Douglas, Andre, Marc, Bellam, Naresh, Goswami, Trishna, Ibrahim, Ramy, Schneider, Amy, Liang, Meina, Eck, Steven, Elgeioushi, Nairouz, Herbst, Ronald, Cheson, Bruce D
Publicado em 2013

Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice

Por Morissette, Mathieu C., Gao, Yang, Shen, Pamela, Thayaparan, Danya, Bérubé, Jean‐Christophe, Paré, Peter D., Brandsma, Corry‐Anke, Hao, Ke, Bossé, Yohan, Ettinger, Rachel, Herbst, Ronald, Humbles, Alison A., Kolbeck, Roland, Zhong, Nanshan, Chen, Rongchang, Stämpfli, Martin R.
Publicado no Physiol Rep (2016)

S100A9 Induced Inflammatory Responses Are Mediated by Distinct Damage Associated Molecular Patterns (DAMP) Receptors In Vitro and In Vivo

Por Chen, Bo, Miller, Allison L., Rebelatto, Marlon, Brewah, Yambasu, Rowe, Daniel C., Clarke, Lori, Czapiga, Meggan, Rosenthal, Kim, Imamichi, Tomozumi, Chen, Yan, Chang, Chew-Shun, Chowdhury, Partha S., Naiman, Brian, Wang, Yue, Yang, De, Humbles, Alison A., Herbst, Ronald, Sims, Gary P.
Publicado no PLoS One (2015)

Autoimmune manifestations in aged mice arise from early-life immune dysregulation

Por Mahmoud, Tamer I., Wang, Jingya, Karnell, Jodi L., Wang, Qiming, Wang, Shu, Naiman, Brian, Gross, Phillip, Brohawn, Philip Z., Morehouse, Chris, Aoyama, Jordan, Wasserfall, Clive, Carter, Laura, Atkinson, Mark A., Serreze, David V., Braley-Mullen, Helen, Mustelin, Tomas, Kolbeck, Roland, Herbst, Ronald, Ettinger, Rachel
Publicado no Sci Transl Med (2016)