B-cell targeted therapeutics in clinical development

Por Blüml, Stephan, McKeever, Kathleen, Ettinger, Rachel, Smolen, Josef, Herbst, Ronald
Publicado em 2013

Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII:...

Por Qi, Yulan, McKeever, Kathleen, Taylor, Julie, Haller, Christine, Song, Wenjie, Jones, Simon A., Shi, Jack
Publicado no Clin Pharmacokinet (2018)

Correction to: Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysacchari...

Por Qi, Yulan, McKeever, Kathleen, Taylor, Julie, Haller, Christine, Song, Wenjie, Jones, Simon A., Shi, Jack
Publicado no Clin Pharmacokinet (2018)

Safety testing of monoclonal antibodies in non-human primates: Case studies highlighting their impact on human risk assessment

Por Brennan, Frank R., Cavagnaro, Joy, McKeever, Kathleen, Ryan, Patricia C., Schutten, Melissa M., Vahle, John, Weinbauer, Gerhard F., Marrer-Berger, Estelle, Black, Lauren E.
Publicado no MAbs (2017)

Choice of Starting Dose for Biopharmaceuticals in First-in-Human Phase I Cancer Clinical Trials

Por Hansen, Aaron R., Cook, Natalie, Ricci, M. Stacey, Razak, Albiruni, Le Tourneau, Christophe, McKeever, Kathleen, Roskos, Lorin, Dixit, Rakesh, Siu, Lillian L., Hinrichs, Mary Jane
Publicado no Oncologist (2015)

Safety and tolerability of an anti-CD19 monoclonal antibody, MEDI-551, in subjects with systemic sclerosis: a phase I, randomized, placebo-controlled, escalating single-dose study

Por Schiopu, Elena, Chatterjee, Soumya, Hsu, Vivien, Flor, Armando, Cimbora, Daniel, Patra, Kaushik, Yao, Wenliang, Li, Jing, Streicher, Katie, McKeever, Kathleen, White, Barbara, Katz, Eliezer, Drappa, Jorn, Sweeny, Sarah, Herbst, Ronald
Publicado no Arthritis Res Ther (2016)