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Loss of Immune Tolerance Is Controlled by ICOS in Sle1 Mice

ICOS, a member of the CD28 family, represents a key molecule that regulates adaptive responses to foreign Ags. ICOS is prominently expressed on T follicular helper (T(FH)) cells, a specialized CD4(+) T cell subset that orchestrates B cell differentiation within the germinal centers and humoral respo...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Mittereder, Nanette, Kuta, Ellen, Bhat, Geetha, Dacosta, Karma, Cheng, Lily I., Herbst, Ronald, Carlesso, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932174/
https://ncbi.nlm.nih.gov/pubmed/27296665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502241
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