B7h (ICOS-L) Maintains Tolerance at the Fetomaternal Interface

In a successful pregnancy, the semiallogeneic fetus is not rejected by the maternal immune system, which implies tolerance mechanisms protecting fetal tissues from maternal immune attack. Here we report that the ICOS-B7h costimulatory pathway plays a critical role in maintaining the equilibrium at t...

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Detalhes bibliográficos
Main Authors: Riella, Leonardo V., Dada, Shirine, Chabtini, Lola, Smith, Brian, Huang, Lei, Dakle, Pranal, Mfarrej, Bechara, D'Addio, Francesca, Adams, La-Tonya, Kochupurakkal, Nora, Vergani, Andrea, Fiorina, Paolo, Mellor, Andrew L., Sharpe, Arlene H., Yagita, Hideo, Guleria, Indira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668017/
https://ncbi.nlm.nih.gov/pubmed/23578385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.014
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