THE LINK BETWEEN PDL1 COSTIMULATORY PATHWAY AND TH17 IN FETOMATERNAL TOLERANCE

Fetomaternal tolerance has been shown to depend both on regulatory T cells (Tregs) and negative signals from the PD1-PDL1 costimulatory pathway. More recently, IL-17-producing T cells (Th17) have been recognized as a barrier in inducing tolerance in transplantation. Herein we investigate the mechani...

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Detalhes bibliográficos
Main Authors: D'Addio, Francesca, Riella, Leonardo V., Mfarrej, Bechara G., Chabtini, Lola, Adams, La Tonya, Yeung, Melissa, Yagita, Hideo, Azuma, Miyuki, Sayegh, Mohamed H., Guleria, Indira
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197965/
https://ncbi.nlm.nih.gov/pubmed/21949023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002031
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