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Anti-CD3 treatment cures PDL1−/−.NOD mice of diabetes but precipitates fatal myocarditis
Anti-CD3 mAb is an effective therapy that can reverse diabetes in NOD mice and has therapeutic potential in patients with type 1 diabetes (T1D). We administered anti-CD3 to PDL1−/−.NOD mice in order to determine whether this treatment would reverse the development of diabetes in these mice. Mice inj...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730534/ https://ncbi.nlm.nih.gov/pubmed/21498129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.03.011 |
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