The Net Repressor Is Regulated by Nuclear Export in Response to Anisomycin, UV, and Heat Shock

Por Ducret, Catherine, Maira, Sauveur-Michel, Dierich, Andrée, Wasylyk, Bohdan
Publicado em 1999

Domain Swapping Used To Investigate the Mechanism of Protein Kinase B Regulation by 3-Phosphoinositide-Dependent Protein Kinase 1 and Ser473 Kinase

Por Andjelković, Mirjana, Maira, Sauveur-Michel, Cron, Peter, Parker, Peter J., Hemmings, Brian A.
Publicado em 1999

Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome

Por Wang, Qi, Von, Thanh, Bronson, Roderick, Ruan, Minzi, Mu, Wenxia, Huang, Alan, Maira, Sauveur-Michel, Zhao, Jean J.
Publicado em 2013

PTEN-deficient cancers depend on PIK3CB

Por Wee, Susan, Wiederschain, Dmitri, Maira, Sauveur-Michel, Loo, Alice, Miller, Christine, deBeaumont, Rosalie, Stegmeier, Frank, Yao, Yung-Mae, Lengauer, Christoph
Publicado em 2008

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

Por Brachmann, Saskia M., Hofmann, Irmgard, Schnell, Christian, Fritsch, Christine, Wee, Susan, Lane, Heidi, Wang, Shaowen, Garcia-Echeverria, Carlos, Maira, Sauveur-Michel
Publicado em 2009

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

Por Dubrovska, Anna, Kim, Sungeun, Salamone, Richard J., Walker, John R., Maira, Sauveur-Michel, García-Echeverría, Carlos, Schultz, Peter G., Reddy, Venkateshwar A.
Publicado em 2009

The transcription factor Net regulates the angiogenic switch

Por Zheng, Hong, Wasylyk, Christine, Ayadi, Abdelkader, Abecassis, Joseph, Schalken, Jack A, Rogatsch, Hermann, Wernert, Nicolas, Maira, Sauveur-Michel, Multon, Marie-Christine, Wasylyk, Bohdan
Publicado em 2003

NVP-BEZ235, A Novel Dual PI3K/mTOR Inhibitor, Elicits Multifaceted Antitumor Activities in Human Gliomas

Por Liu, Ta-Jen, Koul, Dimpy, LaFortune, Tiffany, Tiao, Ningyi, Shen, Rui Jun, Maira, Sauveur-Michel, Garcia-Echevrria, Carlos, Alfred Yung, W. K.
Publicado em 2009

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity

Por Fokas, Emmanouil, Yoshimura, Michio, Prevo, Remko, Higgins, Geoff, Hackl, Wolfgang, Maira, Sauveur-Michel, Bernhard, Eric J, McKenna, W Gillies, Muschel, Ruth J
Publicado em 2012

Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells

Por Zito, Christopher R., Jilaveanu, Lucia B., Anagnostou, Valsamo, Rimm, David, Bepler, Gerold, Maira, Sauveur-Michel, Hackl, Wolfgang, Camp, Robert, Kluger, Harriet M., Chao, Herta H.
Publicado em 2012

Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention

Por Jia, Shidong, Gao, Xueliang, Lee, Sang Hyun, Maira, Sauveur-Michel, Wu, Xiaoqiu, Stack, Edward C., Signoretti, Sabina, Loda, Massimo, Zhao, Jean J, Roberts, Thomas M.
Publicado em 2012

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

Por Faber, Anthony C., Li, Danan, Song, YoungChul, Liang, Mei-Chih, Yeap, Beow Y., Bronson, Roderick T., Lifshits, Eugene, Chen, Zhao, Maira, Sauveur-Michel, García-Echeverría, Carlos, Wong, Kwok-Kin, Engelman, Jeffrey A.
Publicado em 2009

Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α

Por Gritsman, Kira, Yuzugullu, Haluk, Von, Thanh, Yan, Howard, Clayton, Linda, Fritsch, Christine, Maira, Sauveur-Michel, Hollingworth, Gregory, Choi, Christine, Khandan, Tulasi, Paktinat, Mahnaz, Okabe, Rachel O., Roberts, Thomas M., Zhao, Jean J.
Publicado em 2014

K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

Por Hofmann, Irmgard, Weiss, Andreas, Elain, Gaelle, Schwaederle, Maria, Sterker, Dario, Romanet, Vincent, Schmelzle, Tobias, Lai, Albert, Brachmann, Saskia M., Bentires-Alj, Mohamed, Roberts, Thomas M., Sellers, William R., Hofmann, Francesco, Maira, Sauveur-Michel
Publicado em 2012

Antitumor Activity of NVP-BKM120–A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells

Por Koul, Dimpy, Fu, Jun, Shen, Ruijun, LaFortune, Tiffany A., Wang, Shuzhen, Tiao, Ningyi, Kim, Yong-Wan, Liu, Juinn-Lin, Ramnarian, Deepti, Yuan, Ying, Garcia-Echevrria, Carlos, Maira, Sauveur-Michel, Yung, W.K. Alfred
Publicado em 2011

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 is highly responsive to mTOR inhibition

Por Cheng, Hailing, Liu, Pixu, Zhang, Fan, Xu, Erbo, Symonds, Lynn, Ohlson, Carolynn E., Bronson, Roderick T., Maira, Sauveur-Michel, Tomaso, Emmanuelle Di, Li, Jane, Myers, Andrea P., C.Cantley, Lewis, Mills, Gordon B., Zhao, Jean J.
Publicado em 2013

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

Por Sack Ragna, Hess Daniel, Chun Taehoon, Cho Jae Youl, Seok Jeong Ho, Hur Gang Min, Kweon Gi Ryang, Kim Jeong-Lan, Hong Janghee, Won Minho, Byun Hee Sun, Park Kyeong Ah, Yang Keum-Jin, Li Yuwen, Piao Longzhen, Maira Sauveur-Michel, Brazil Derek P, Hemmings Brian A, Park Jongsun
Publicado em 2009-07-01

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

Por Piao, Longzhen, Li, Yuwen, Yang, Keum-Jin, Park, Kyeong Ah, Byun, Hee Sun, Won, Minho, Hong, Janghee, Kim, Jeong-Lan, Kweon, Gi Ryang, Hur, Gang Min, Seok, Jeong Ho, Cho, Jae Youl, Chun, Taehoon, Hess, Daniel, Sack, Ragna, Maira, Sauveur-Michel, Brazil, Derek P, Hemmings, Brian A, Park, Jongsun
Publicado em 2009

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

Por Miller, Todd W., Balko, Justin M., Fox, Emily M., Ghazoui, Zara, Dunbier, Anita, Anderson, Helen, Dowsett, Mitch, Jiang, Aixiang, Smith, R. Adam, Maira, Sauveur-Michel, Manning, H. Charles, González-Angulo, Ana M., Mills, Gordon B., Higham, Catherine, Chanthaphaychith, Siprachanh, Kuba, Maria G., Miller, William R., Shyr, Yu, Arteaga, Carlos L.
Publicado em 2011

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Por Burger, Matthew T., Pecchi, Sabina, Wagman, Allan, Ni, Zhi-Jie, Knapp, Mark, Hendrickson, Thomas, Atallah, Gordana, Pfister, Keith, Zhang, Yanchen, Bartulis, Sarah, Frazier, Kelly, Ng, Simon, Smith, Aaron, Verhagen, Joelle, Haznedar, Joshua, Huh, Kay, Iwanowicz, Ed, Xin, Xiaohua, Menezes, Daniel, Merritt, Hanne, Lee, Isabelle, Wiesmann, Marion, Kaufman, Susan, Crawford, Kenneth, Chin, Michael, Bussiere, Dirksen, Shoemaker, Kevin, Zaror, Isabel, Maira, Sauveur-Michel, Voliva, Charles F.
Publicado em 2011