Llwytho...
NVP-BEZ235, A Novel Dual PI3K/mTOR Inhibitor, Elicits Multifaceted Antitumor Activities in Human Gliomas
Aberrant genetic alternations in human gliomas such as amplification of EGFR, mutation and/or deletion of tumor suppressor gene PTEN, and mutations of PIK3CA contribute to constitutive activation of the PI3K pathway. We investigated the potential anti-tumor activity of NVP-BEZ235, which is a novel d...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2009
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752877/ https://ncbi.nlm.nih.gov/pubmed/19671762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0160 |
| Tagiau: |
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