NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma

Osteosarcoma(OS) remains a major health concern in childhood and adolescence, although cisplatin is one of the gold standard chemotherapeutic drugs in the treatment of OS, chemoresistant to cisplatin is common. Phosphoinositide 3-kinase (PI3K)-Akt-mammalian target of rapamycin inhibitor (mTOR) pathw...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Huang, Jin-Cheng, Cui, Zhi-Fei, Chen, Shui-Mu, Yang, Lian-Jun, Lian, Hong-Kai, Liu, Bin, Su, Zhi-Hai, Liu, Jin-Shi, Wang, Min, Hu, Zheng-Bo, Ouyang, Jia-Yao, Li, Qing-Chu, Lu, Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828183/
https://ncbi.nlm.nih.gov/pubmed/29535821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23711
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