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PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer

Colon cancer is the third most common cancer in humans which has a high mortality rate, and 5-Fluorouracil (5-FU) is one of the most widely used drugs in colon cancer therapy. However, acquired chemoresistance is becoming the major challenges for patients, and the molecular mechanism underlying the...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Wang, Huanan, Zhang, Lingling, Yang, Xu, Jin, Yipeng, Pei, Shimin, Zhang, Di, Zhang, Hong, Zhou, Bin, Zhang, Yingjie, Lin, Degui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546474/
https://ncbi.nlm.nih.gov/pubmed/25965911
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