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The Synergistic Anti-Cancer Effects of NVP-BEZ235 and Regorafenib in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. Regorafenib is a multi-kinase inhibitor and the second-line treatment for HCC. Since the PI3K/Akt/mTOR signaling pathway is dysregulated in HCC, we evaluated the therapeutic effects of regorafenib combined with a dual...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yu, Cheng-Chan, Huang, Sung-Ying, Chang, Shu-Fang, Liao, Kuan-Fu, Chiu, Sheng-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287658/
https://ncbi.nlm.nih.gov/pubmed/32466169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102454
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