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The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer

Gastric cancer is the second most common cause of cancer-related deaths worldwide. Taxanes have shown therapeutic effects against gastric cancer while also activating the PI3K/mTOR signaling pathway. We investigated the effects of NVP-BEZ235 (BEZ235), a novel dual PI3K/mTOR inhibitor, alone and in c...

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Detalhes bibliográficos
Main Authors: ZHANG, CHANG-HUA, AWASTHI, NIRANJAN, SCHWARZ, MARGARET A., SCHWARZ, RODERICH E.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144025/
https://ncbi.nlm.nih.gov/pubmed/24042258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2099
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