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Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention

Prostate cancer is an ideal target for chemoprevention. To date, chemoprevention clinical trials with 5α-reductase inhibitors (5-ARI) have yielded encouraging yet ultimately confounding results. Using a pre-clinical mouse model of high-grade prostatic intraepithelial neoplasia (HG-PIN) induced by PT...

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Detalhes bibliográficos
Main Authors: Jia, Shidong, Gao, Xueliang, Lee, Sang Hyun, Maira, Sauveur-Michel, Wu, Xiaoqiu, Stack, Edward C., Signoretti, Sabina, Loda, Massimo, Zhao, Jean J, Roberts, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546223/
https://ncbi.nlm.nih.gov/pubmed/23258246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0262
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