Actionability and precision oncology

Por Schwaederle, Maria, Kurzrock, Razelle
Publicado no Oncoscience (2015)

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications

Por Helsten, Teresa, Schwaederle, Maria, Kurzrock, Razelle
Publicado no Cancer Metastasis Rev (2015)

An appraisal of drug development timelines in the Era of precision oncology

Por Jardim, Denis Leonardo, Schwaederle, Maria, Hong, David S., Kurzrock, Razelle
Publicado no Oncotarget (2016)

HER2 expression status in diverse cancers: review of results from 37,992 patients

Por Yan, Min, Schwaederle, Maria, Arguello, David, Millis, Sherri Z., Gatalica, Zoran, Kurzrock, Razelle
Publicado no Cancer Metastasis Rev (2015)

Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor types

Por Schwaederle, Maria, Elkin, Sheryl K, Tomson, Brett N, Carter, Jennifer Levin, Kurzrock, Razelle
Publicado no Cell Cycle (2015)

Genomic landscape of salivary gland tumors

Por Kato, Shumei, Elkin, Sheryl K., Schwaederle, Maria, Tomson, Brett N., Helsten, Teresa, Carter, Jennifer L., Kurzrock, Razelle
Publicado no Oncotarget (2015)

Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials

Por Schwaederle, Maria, Zhao, Melissa, Lee, J. Jack, Eggermont, Alexander M., Schilsky, Richard L., Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle
Publicado no J Clin Oncol (2015)

Cyclin alterations in diverse cancers: outcome and co-amplification network

Por Schwaederlé, Maria, Daniels, Gregory A., Piccioni, David E., Fanta, Paul T., Schwab, Richard B., Shimabukuro, Kelly A., Parker, Barbara A., Kurzrock, Razelle
Publicado no Oncotarget (2014)

Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Por Kato, Shumei, Schwaederle, Maria, Daniels, Gregory A, Piccioni, David, Kesari, Santosh, Bazhenova, Lyudmila, Shimabukuro, Kelly, Parker, Barbara A, Fanta, Paul, Kurzrock, Razelle
Publicado no Cell Cycle (2015)

Next generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer

Por Schwaederle, Maria, Daniels, Gregory A, Piccioni, David E, Kesari, Santosh, Fanta, Paul T, Schwab, Richard B, Shimabukuro, Kelly A, Parker, Barbara A, Kurzrock, Razelle
Publicado no Cell Cycle (2015)

Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-Analysis of Clinical Trials Leading to FDA Approval

Por Fontes Jardim, Denis L., Schwaederle, Maria, Wei, Caimiao, Lee, J. Jack, Hong, David S., Eggermont, Alexander M., Schilsky, Richard L., Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle
Publicado no J Natl Cancer Inst (2015)

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay

Por Schwaederle, Maria, Husain, Hatim, Fanta, Paul T., Piccioni, David E., Kesari, Santosh, Schwab, Richard B., Banks, Kimberly C., Lanman, Richard B., Talasaz, AmirAli, Parker, Barbara A., Kurzrock, Razelle
Publicado no Oncotarget (2016)

Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21(WAF1/Cip1)-dependent mechanism independent of functional p53

Por Fecteau, Jessie-F., Corral, Laura G., Ghia, Emanuela M., Gaidarova, Svetlana, Futalan, Diahnn, Bharati, Ila Sri, Cathers, Brian, Schwaederlé, Maria, Cui, Bing, Lopez-Girona, Antonia, Messmer, Davorka, Kipps, Thomas J.
Publicado em 2014

K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

Por Hofmann, Irmgard, Weiss, Andreas, Elain, Gaelle, Schwaederle, Maria, Sterker, Dario, Romanet, Vincent, Schmelzle, Tobias, Lai, Albert, Brachmann, Saskia M., Bentires-Alj, Mohamed, Roberts, Thomas M., Sellers, William R., Hofmann, Francesco, Maira, Sauveur-Michel
Publicado em 2012

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology

Por Patel, Sandip P., Schwaederle, Maria, Daniels, Gregory A., Fanta, Paul T., Schwab, Richard B., Shimabukuro, Kelly A., Kesari, Santosh, Piccioni, David E., Bazhenova, Lyudmila A., Helsten, Teresa L., Lippman, Scott M., Parker, Barbara A., Kurzrock, Razelle
Publicado no Oncotarget (2015)

Molecular Tumor Board: The University of California San Diego Moores Cancer Center Experience

Por Schwaederle, Maria, Parker, Barbara A., Schwab, Richard B., Fanta, Paul T., Boles, Sarah G., Daniels, Gregory A., Bazhenova, Lyudmila A., Subramanian, Rupa, Coutinho, Alice C., Ojeda-Fournier, Haydee, Datnow, Brian, Webster, Nicholas J., Lippman, Scott M., Kurzrock, Razelle
Publicado em 2014

Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms

Por Wheler, Jennifer J., Parker, Barbara A., Lee, Jack J., Atkins, Johnique T., Janku, Filip, Tsimberidou, Apostolia M., Zinner, Ralph, Subbiah, Vivek, Fu, Siqing, Schwab, Richard, Moulder, Stacy, Valero, Vicente, Schwaederle, Maria, Yelensky, Roman, Miller, Vincent A., Stephens, M Philip J., Meric-Bernstam, Funda, Kurzrock, Razelle
Publicado em 2014