Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Aberrations in the cyclin-dependent kinase (CDK) pathways that regulate the cell cycle restriction point contribute to genomic instability and tumor proliferation, and can be targeted by recently developed CDK inhibitors. We therefore investigated the clinical correlates of CDK4/6 and CDKN2A/B abnor...

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Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Kato, Shumei, Schwaederle, Maria, Daniels, Gregory A, Piccioni, David, Kesari, Santosh, Bazhenova, Lyudmila, Shimabukuro, Kelly, Parker, Barbara A, Fanta, Paul, Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614867/
https://ncbi.nlm.nih.gov/pubmed/25695927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1014149
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