Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Aberrations in the cyclin-dependent kinase (CDK) pathways that regulate the cell cycle restriction point contribute to genomic instability and tumor proliferation, and can be targeted by recently developed CDK inhibitors. We therefore investigated the clinical correlates of CDK4/6 and CDKN2A/B abnor...

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Publicat a:Cell Cycle
Autors principals: Kato, Shumei, Schwaederle, Maria, Daniels, Gregory A, Piccioni, David, Kesari, Santosh, Bazhenova, Lyudmila, Shimabukuro, Kelly, Parker, Barbara A, Fanta, Paul, Kurzrock, Razelle
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614867/
https://ncbi.nlm.nih.gov/pubmed/25695927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1014149
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