Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Aberrations in the cyclin-dependent kinase (CDK) pathways that regulate the cell cycle restriction point contribute to genomic instability and tumor proliferation, and can be targeted by recently developed CDK inhibitors. We therefore investigated the clinical correlates of CDK4/6 and CDKN2A/B abnor...

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Publicado en:Cell Cycle
Main Authors: Kato, Shumei, Schwaederle, Maria, Daniels, Gregory A, Piccioni, David, Kesari, Santosh, Bazhenova, Lyudmila, Shimabukuro, Kelly, Parker, Barbara A, Fanta, Paul, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614867/
https://ncbi.nlm.nih.gov/pubmed/25695927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1014149
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