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Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications

Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival. FGFR germline mutations (activating) can cause skel...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Helsten, Teresa, Schwaederle, Maria, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573649/
https://ncbi.nlm.nih.gov/pubmed/26224133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-015-9579-8
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