NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations

Inactivating germline mutations in the tumor suppressor gene NF2 cause the hereditary syndrome neurofibromatosis 2, which is characterized by the development of neoplasms of the nervous system, most notably bilateral vestibular schwannoma. Somatic NF2 mutations have also been reported in a variety o...

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Detaylı Bibliyografya
Asıl Yazarlar: Schroeder, Rebecca Dunbar, Angelo, Laura S., Kurzrock, Razelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2013
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960189/
https://ncbi.nlm.nih.gov/pubmed/24393766
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