GNAS Mutations Identify a Set of Right-Sided, RAS Mutant, Villous Colon Cancers

por Fecteau, Ryan E., Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph, Guda, Kishore
Publicado 2014

Genetic Variation in 15-Hydroxyprostaglandin Dehydrogenase and Colon Cancer Susceptibility

por Thompson, Cheryl L., Fink, Stephen P., Lutterbaugh, James D., Elston, Robert C., Veigl, Martina L., Markowitz, Sanford D., Li, Li
Publicado 2013

Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies

por Moinova, Helen, Leidner, Rom S., Ravi, Lakshmeswari, Lutterbaugh, James, Barnholtz-Sloan, Jill S., Chen, Yanwen, Chak, Amitabh, Markowitz, Sanford D., Willis, Joseph E.
Publicado 2012

ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients

por Varadan, Vinay, Singh, Salendra, Nosrati, Arman, Ravi, Lakshmeswari, Lutterbaugh, James, Barnholtz-Sloan, Jill S., Markowitz, Sanford D., Willis, Joseph E., Guda, Kishore
Publicado en Genome Med (2015)

NTRK3 Is a Potential Tumor Suppressor Gene Commonly Inactivated by Epigenetic Mechanisms in Colorectal Cancer

por Luo, Yanxin, Kaz, Andrew M., Kanngurn, Samornmas, Welsch, Piri, Morris, Shelli M., Wang, Jianping, Lutterbaugh, James D., Markowitz, Sanford D., Grady, William M.
Publicado 2013

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer

por Venkitachalam, Srividya, Revoredo, Leslie, Varadan, Vinay, Fecteau, Ryan E., Ravi, Lakshmeswari, Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph E., Gerken, Thomas A., Guda, Kishore
Publicado en Sci Rep (2016)

A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2

por Wiesner, Georgia L., Daley, Denise, Lewis, Susan, Ticknor, Christine, Platzer, Petra, Lutterbaugh, James, MacMillen, Melissa, Baliner, Boris, Willis, Joseph, Elston, Robert C., Markowitz, Sanford D.
Publicado 2003

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers

por Veigl, Martina L., Kasturi, Lakshmi, Olechnowicz, Joseph, Ma, AiHong, Lutterbaugh, James D., Periyasamy, Sumudra, Li, Guo-Min, Drummond, James, Modrich, Paul L., Sedwick, W. David, Markowitz, Sanford D.
Publicado 1998

Infrequent Detection of Germline Allele-Specific Expression of TGFBR1 in Lymphoblasts and Tissues of Colon Cancer Patients

por Guda, Kishore, Natale, Leanna, Lutterbaugh, James, Wiesner, Georgia L., Lewis, Susan, Tanner, Stephan M., Tomsic, Jerneja, Valle, Laura, de la Chapelle, Albert, Elston, Robert C., Willis, Joseph, Markowitz, Sanford D.
Publicado 2009

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites

por Balasubramanian, Dheepa, Akhtar-Zaidi, Batool, Song, Lingyun, Bartels, Cynthia F, Veigl, Martina, Beard, Lydia, Myeroff, Lois, Guda, Kishore, Lutterbaugh, James, Willis, Joseph, Crawford, Gregory E, Markowitz, Sanford D, Scacheri, Peter C
Publicado 2012

SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

por Li, Hui, Myeroff, Lois, Smiraglia, Dominic, Romero, Michael F., Pretlow, Theresa P., Kasturi, Lakshmi, Lutterbaugh, James, Rerko, Ronald M., Casey, Graham, Issa, Jean-Pierre, Willis, Joseph, Willson, James K. V., Plass, Christoph, Markowitz, Sanford D.
Publicado 2003

15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-β-induced suppressor of human gastrointestinal cancers

por Yan, Min, Rerko, Ronald M., Platzer, Petra, Dawson, Dawn, Willis, Joseph, Tong, Min, Lawrence, Earl, Lutterbaugh, James, Lu, Shilong, Willson, James K. V., Luo, Guangbin, Hensold, Jack, Tai, Hsin-Hsiung, Wilson, Keith, Markowitz, Sanford D.
Publicado 2004

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors

por Yan, Min, Myung, Seung-Jae, Fink, Stephen P., Lawrence, Earl, Lutterbaugh, James, Yang, Peiying, Zhou, Xiaohua, Liu, Danielle, Rerko, Ronald M., Willis, Joseph, Dawson, Dawn, Tai, Hsin-Hsiung, Barnholtz-Sloan, Jill S., Newman, Robert A., Bertagnolli, Monica M., Markowitz, Sanford D.
Publicado 2009

Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression from Adenoma to Colorectal Cancer

por Luo, Yanxin, Wong, Chao-Jen, Kaz, Andrew M., Dzieciatkowski, Slavomir, Carter, Kelly T., Morris, Shelli M., Wang, Jianping, Willis, Joseph E., Makar, Karen W., Ulrich, Cornelia M., Lutterbaugh, James D., Shrubsole, Martha J., Zheng, Wei, Markowitz, Sanford D., Grady, William M.
Publicado 2014

Novel recurrently mutated genes in African American colon cancers

por Guda, Kishore, Veigl, Martina L., Varadan, Vinay, Nosrati, Arman, Ravi, Lakshmeswari, Lutterbaugh, James, Beard, Lydia, Willson, James K. V., Sedwick, W. David, Wang, Zhenghe John, Molyneaux, Neil, Miron, Alexander, Adams, Mark D., Elston, Robert C., Markowitz, Sanford D., Willis, Joseph E.
Publicado en Proc Natl Acad Sci U S A (2015)

Reply to Ashktorab et al.: Mutational landscape of colon cancers in African Americans

por Guda, Kishore, Veigl, Martina L., Varadan, Vinay, Nosrati, Arman, Ravi, Lakshmeswari, Lutterbaugh, James, Beard, Lydia, Willson, James K. V., Sedwick, W. David, Wang, Zhenghe John, Molyneaux, Neil, Miron, Alexander, Adams, Mark D., Elston, Robert C., Markowitz, Sanford D., Willis, Joseph E.
Publicado en Proc Natl Acad Sci U S A (2015)

Epigenomic enhancer profiling defines a signature of colon cancer

por Akhtar-Zaidi, Batool, Cowper-Sal·lari, Richard, Corradin, Olivia, Saiakhova, Alina, Bartels, Cynthia F., Balasubramanian, Dheepa, Myeroff, Lois, Lutterbaugh, James, Jarrar, Awad, Kalady, Matthew F., Willis, Joseph, Moore, Jason H., Tesar, Paul J., Laframboise, Thomas, Markowitz, Sanford, Lupien, Mathieu, Scacheri, Peter C.
Publicado 2012

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

por Overman, Michael J., Morris, Van, Moinova, Helen, Manyam, Ganiraju, Ensor, Joe, Lee, Michael S., Eng, Cathy, Kee, Bryan, Fogelman, David, Shroff, Rachna T., LaFramboise, Thomas, Mazard, Thibault, Feng, Tian, Hamilton, Stanley, Broom, Bradley, Lutterbaugh, James, Issa, Jean-Pierre, Markowitz, Sanford D., Kopetz, Scott
Publicado en Oncotarget (2016)

Identifying DNA Methylation Biomarkers for Non-Endoscopic Detection of Barrett’s Esophagus

por Moinova, Helen R., LaFramboise, Thomas, Lutterbaugh, James D., Chandar, Apoorva Krishna, Dumot, John, Faulx, Ashley, Brock, Wendy, De la Cruz Cabrera, Omar, Guda, Kishore, Barnholtz-Sloan, Jill S., Iyer, Prasad G., Canto, Marcia I., Wang, Jean S., Shaheen, Nicholas J., Thota, Prashanti N., Willis, Joseph E., Chak, Amitabh, Markowitz, Sanford D.
Publicado en Sci Transl Med (2018)

Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers

por Guda, Kishore, Moinova, Helen, He, Jian, Jamison, Oliver, Ravi, Lakshmeswari, Natale, Leanna, Lutterbaugh, James, Lawrence, Earl, Lewis, Susan, Willson, James K. V., Lowe, John B., Wiesner, Georgia L., Parmigiani, Giovanni, Barnholtz-Sloan, Jill, Dawson, Dawn W., Velculescu, Victor E., Kinzler, Kenneth W., Papadopoulos, Nikolas, Vogelstein, Bert, Willis, Joseph, Gerken, Thomas A., Markowitz, Sanford D.
Publicado 2009