Epigenomic enhancer profiling defines a signature of colon cancer

Cancer is characterized by gene expression aberrations. Studies have largely focused on coding sequences and promoters, despite the fact that distal regulatory elements play a central role in controlling transcription patterns. Here we utilize the histone mark H3K4me1 to analyze gain and loss of enh...

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Main Authors: Akhtar-Zaidi, Batool, Cowper-Sal·lari, Richard, Corradin, Olivia, Saiakhova, Alina, Bartels, Cynthia F., Balasubramanian, Dheepa, Myeroff, Lois, Lutterbaugh, James, Jarrar, Awad, Kalady, Matthew F., Willis, Joseph, Moore, Jason H., Tesar, Paul J., Laframboise, Thomas, Markowitz, Sanford, Lupien, Mathieu, Scacheri, Peter C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711120/
https://ncbi.nlm.nih.gov/pubmed/22499810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217277
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