Epigenomic enhancer profiling defines a signature of colon cancer

Cancer is characterized by gene expression aberrations. Studies have largely focused on coding sequences and promoters, despite the fact that distal regulatory elements play a central role in controlling transcription patterns. Here we utilize the histone mark H3K4me1 to analyze gain and loss of enh...

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Библиографические подробности
Главные авторы: Akhtar-Zaidi, Batool, Cowper-Sal·lari, Richard, Corradin, Olivia, Saiakhova, Alina, Bartels, Cynthia F., Balasubramanian, Dheepa, Myeroff, Lois, Lutterbaugh, James, Jarrar, Awad, Kalady, Matthew F., Willis, Joseph, Moore, Jason H., Tesar, Paul J., Laframboise, Thomas, Markowitz, Sanford, Lupien, Mathieu, Scacheri, Peter C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711120/
https://ncbi.nlm.nih.gov/pubmed/22499810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217277
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