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Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer

The molecular basis of aberrant protein glycosylation, a pathological alteration widespread in colorectal cancers (CRC), and the mechanisms by which it contributes to tumor progression remain largely unknown. We performed targeted re-sequencing of 430 glycosylation-associated genes in a series of pa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Venkitachalam, Srividya, Revoredo, Leslie, Varadan, Vinay, Fecteau, Ryan E., Ravi, Lakshmeswari, Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph E., Gerken, Thomas A., Guda, Kishore
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804330/
https://ncbi.nlm.nih.gov/pubmed/27004849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23642
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