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GNAS Mutations Identify a Set of Right-Sided, RAS Mutant, Villous Colon Cancers

The purpose of this study is to determine the genetic frequency of GNAS activating mutations in colorectal cancer and the corresponding pathology of GNAS mutant tumors. Oncogenic mutations in GNAS have been described in a number of neoplasms including those of the pituitary, kidney, pancreas, and, m...

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Detalhes bibliográficos
Main Authors: Fecteau, Ryan E., Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph, Guda, Kishore
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907576/
https://ncbi.nlm.nih.gov/pubmed/24498230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087966
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